The news was confirmed in a tweet by the Nigeria Football Federation (NFF).
They confirmed that the Galatasaray midfielder will not play a part in the matches against Algeria and Tunisia on October 9 and 13 respectively.
The 24-year-old had been named in Gernot Rohr’s squad that will take on the North African countries as part of preparations for their Africa Cup of Nations qualifying games against Sierra Leone in November.
Etebo only recently joined Galatasaray in September on a season-long loan from Championship side Stoke City.
The midfielder picked up a knock in his first game, a defeat against Kasımpasa on Sunday.
The 24-year-old has now pulled out of the Super Eagles friendlies in Austria due to the problem and a replacement will be expected to be named soon.
“Super Eagles midfielder Etebo is out of the friendly games against Algeria and Tunisia. He picked up a knock in his club’s game in Turkey yesterday,” read a tweet from NFF.
Etebo did not mention his injury during his reaction to his side’s defeat on Sunday.
“Of course, my good performance doesn’t mean much individually. We wanted to win. Our performance as a team was very important, but we could not show the performance we wanted,” he told the club website.
“Now is not the time to be sad, we have matches ahead of us. We need to put this match aside and focus on other matches and prepare for them in the best way possible.
“We are incredibly unhappy right now, including me. We did not expect such a score. There are many more matches ahead. That’s why we should put this match aside and focus on them.”
The midfielder, who spent the second half of last season in Spain with Getafe, also explains he is gradually settling in at the Turkish side
“I’m getting better step by step. It is not easy, you come to a new team, I feel that my adaptation process is getting better every day,” he added.
Etebo has 35 caps for the Super Eagles and was part of the side that finished third at the 2019 Africa Cup of Nations in Egypt.
Napoli striker Victor Osimhen has also been ruled out of the friendlies and Genk forward Paul Onuachu has been named as his replacement.